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Garvey WT, Batterham RL, Bhatta M, et al
The short answer is that clinical trials have reported modest reductions in systolic blood pressure among people taking semaglutide, the active ingredient in Ozempic and Wegovy.[18] This is why the Ozempic blood pressure question keeps coming up as part of the wider cardiovascular picture, rather than as a stand-alone effect
Several other studies have also provided evidence that GLP-1RA can reduce hepatic fat accumulation and reduce steatosis in liver tissue by regulating the expression of genes and proteins related to the fat synthesis pathway [109,110]
GLP-1, Mast Cells, and Immune Response: In addition to their role in pancreatic insulin secretion, GLP-1 receptors are found in certain types of immune cells, including T cells and macrophages.[ref] This is an interesting link between metabolic health and immune health, and microdosing GLP-1 medications is being looked at for preventing immune dysregulation in aging